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抗肝癌化合物库 
Anti-Liver Cancer Compound Library
产品编号: L2193
在全球范围内，肝癌占癌症死亡率第三位。肝癌的主要病因包括乙肝、丙肝、酒精性脂肪性肝炎和非酒精性脂肪性肝炎（NASH）。许多细胞信号通路与肝癌的发生有关，如 PI3K/Akt/mTOR 信号通路，表皮生长因子受体(EGFR)、血管内皮生长因子受体(VEGFR)等 TargetMol 抗肝癌化合物库收集了 2000 种与肝癌相关的化合物，包括已经报道具有肝癌治疗作用的化合物，以及靶向肝癌相关靶点潜在治疗肝癌的化合物，是抗肝癌药物研发的良好工具。
陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。
产品编号: L2193
规格
1 mg
30 μL x 10 mM (in DMSO)
50 μL x 10 mM (in DMSO)
100 μL x 10 mM (in DMSO)
250 μL x 10 mM (in DMSO)
特别折扣
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技术资料
陶术生物化合物库目录(60.2 MB) 
库化合物信息
Excel 
SDF 产品描述
产品描述:
- 2000种与肝癌相关的化合物，可以用于抗肝癌药物研发和药理研究；
- 通路靶点包含PI3K/Akt/mTOR，EGFR, FGFR，Met等；
- 部分化合物已上市或进入临床期；
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
化合物库定制
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化合物库组成
Apoptosis
Autophagy
NF-κB
PI3K
VEGFR
Reactive Oxygen Species
EGFR
Wnt/beta-catenin
mTOR
Akt
p38 MAPK
GSK-3
AMPK
ERK
Endogenous Metabolite
STAT
FGFR
JAK
Raf
CDK
Antibacterial
c-Met/HGFR
PDGFR
Ras
TGF-beta/Smad
Src
FLT
MEK
JNK
COX
MAPK
c-Kit
IκB/IKK
TNF
DNA-PK
DNA/RNA Synthesis
HER
ATM/ATR
S6 Kinase
Parasite
Dehydrogenase
HIV Protease
IL Receptor
Antibiotic
Ferroptosis
Caspase
RIP kinase
ALK
Bcr-Abl
Aurora Kinase
PDK
Mitophagy
Tyrosine Kinases
c-RET
Potassium Channel
NOD
Antifungal
Antioxidant
PKC
IGF-1R
PD-1/PD-L1
PPAR
PARP
Cytochromes P450
Kras
Calcium Channel
Influenza Virus
PI4K
Pim
Rho
IRAK
NO Synthase
ROS
Casein Kinase
Microtubule Associated
PKA
MMP
HDAC
Topoisomerase
Trk receptor
NOD-like Receptor (NLR)
HCV Protease
Mitochondrial Metabolism
Isocitrate Dehydrogenase (IDH)
Lipoxygenase
Nrf2
c-Fms
Virus Protease
Nucleoside Antimetabolite/Analog
Chk
Bcl-2 Family
5-HT Receptor
TAM Receptor
FAK
Interleukin
AChR
Syk
HIF/HIF Prolyl-Hydroxylase
Proteasome
HBV
ROCK
PDE
PTEN
Epigenetic Reader Domain
TLR
p53
NOS
Estrogen/progestogen Receptor
SIK
HSV
Antiviral
SARS-CoV
Beta Amyloid
Sodium Channel
Tyrosinase
Tie-2
Phosphatase
Adrenergic Receptor
E1/E2/E3 Enzyme
Antifection
Prostaglandin Receptor
GABA Receptor
Histone Methyltransferase
Adenosine Receptor
NADPH
Histamine Receptor
CSF-1R
Cholinesterase (ChE)
MNK
P-gp
HSP
Ephrin Receptor
ASK
MELK
Reverse Transcriptase
PLK
HIF
SGK
MLK
Carbonic Anhydrase
Transferase
Integrin
Others
DYRK
RAAS
TOPK
Estrogen Receptor/ERR
Serine Protease
TRP/TRPV Channel
Aryl Hydrocarbon Receptor
DNA Alkylation
Cannabinoid Receptor
ATPase
Chloride channel
DNA Alkylator/Crosslinker
BACE
Glutathione Peroxidase
GTPase
c-Myc
Glucocorticoid Receptor
LDL
Gamma-secretase
Glucosidase
Opioid Receptor
CCR
CaMK
PGE Synthase
Porcupine
LRRK2
Sirtuin
transporter
KLF
Discoidin Domain Receptor (DDR)
Anti-infection
ROS Kinase
ADC Cytotoxin
BTK
Mdm2
Proton pump
RAR/RXR
DHFR
Dopamine Receptor
IFNAR
Histone Demethylase
Cholecystokinin Receptor
Hck
Serine/threonin kinase
Leukotriene Receptor
PYK2
RANKL/RANK
MAO
Drug Metabolite
DPP-4
Hedgehog/Smoothened
Somatostatin
cAMP
Lipid
Beta-Secretase
Free radical scavengers
Histone Acetyltransferase
Pyroptosis
RSV
GST
Retinoid Receptor
Aromatase
Phospholipase
NADPH-oxidase
HMG-CoA Reductase
S1P Receptor
Kinesin
Melanin-concentrating Hormone Receptor (MCHR)
Adenylyl Cyclase
NPC1L1
ROR
NEDD8
Arginase
YAP
LTR
Reductase
Na+/Ca2+ Exchanger
PERK
gp120/CD4
Progesterone Receptor
OCT
MRP
Antifolate
Serotonin Transporter
Cysteine Protease
Liver X Receptor
FXR
Glucokinase
IAP
Myosin
IRE1
UGT
Haspin Kinase
ABC Transporter
Monoamine Transporter
Fatty Acid Synthase
PAK
FAAH
ACK1
KSP
GluR
Thrombopoietin Receptor
DNA
DUB
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
SGLT
ATP Citrate Lyase
Wee1
BCRP
OXPHOS
Glutathione reductase
Acyltransferase
STING
Aminopeptidase
Decarboxylase
cGAS
hCE
PAI-1
Methionine Adenosyltransferase (MAT)
Hippo pathway
GPX
CRISPR/Cas9
Hydroxylase
Adenosine Deaminase
Complement System
DAPK
Gap Junction Protein
Platelet aggregation
DNA Methyltransferase
BMI-1
Sigma receptor
Thrombin
AhR
CFTR
PKM
Monoamine Oxidase
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