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抗癌上市药物库 
Anti-Cancer Approved Drug Library
产品编号: L2110
尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功，但癌症仍然是人类面临的巨大挑战，给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征，表现出无限的增殖潜能，维持自身生长信号的持续稳定，逃避应激信号诱导的细胞凋亡，刺激血管生长，为肿瘤提供营养，同时逃避免疫系统防御和诱导局部慢性炎症，发挥其侵袭和转移能力，表现出异常的代谢活动，并通过突变和表观遗传机制显著改变全基因组的稳定性。 根据文献报道和有关公开资料，我们挑选了1800 个具有抗癌活性或潜在抗癌活性的上市药物组成抗癌上市药物库，可用于具体癌症的阳性对照及不同癌症之间相关性研究。如果您对癌症相关适应症感兴趣，还可以关注我们其他三个库：抗癌分子库，癌细胞分化分子库，以及抗癌临床药物库。希望我们在抗癌研究的路上，助您一臂之力！
陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。
产品编号: L2110
规格
1 mg
30 μL x 10 mM (in DMSO)
50 μL x 10 mM (in DMSO)
100 μL x 10 mM (in DMSO)
250 μL x 10 mM (in DMSO)
特别折扣
等您来询问！
等您来询问！
技术资料
陶术生物化合物库目录(60.2 MB) 
库化合物信息
Excel 
SDF 产品描述
产品描述:
- 1800个具有抗癌活性小分子的独特集合，所有化合物都经过了严格的临床前研究和临床试验，由FDA、EMA或NMPA批准上市，可用于高通量、高内涵筛选。
- 所有化合物都具有已知且良好的生物活性、安全性和生物利用度，这些特性可显着加速药物开发和优化，是进行癌症相关研究和药物重定位有效的筛选工具。
- 作用靶点涉及PI3K、HDAC、mTOR、CDK、JAK 等癌症相关靶点，涉及的研究领域包括肺癌、乳腺癌、白血病、淋巴瘤等癌症;
- 结构多样，药效显著，可渗透细胞；
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
化合物库定制
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