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抗COVID-19化合物库 
Anti-COVID-19 Compound Library
产品编号: L1710
为应对COVID-19疫情所造成的全球公共卫生危机，相关部门即出台相应政策支持针对 COVID-19的快速诊断试剂研发及相关治疗药物研发，包括已上市药物的筛选验证及中成药和天然药物有效成分的筛选验证研究、抗体/疫苗类新药研发等。 TargetMol 作为药筛领域的专家，快速研究并推出了适合此次疫情的抗COVID-19化合物库，包含Part1和Part2两部分： Part1为目前公开报道的对其有抑制作用或潜在抑制作用的化合物以及其他相关抗病毒药物，其中有 Lopinavir/Ritonavir（克力芝）、Chloroquine diphosphate（二磷酸氯喹，与Remdesivir 联用）、Polydatin（虎杖苷，与Mpro 结合较好，可能对病毒有抑制作用）等化合物； 另外，基于分子对接的虚拟筛选工作有望快速筛选出高亲和力的靶向小分子药物，可为抗SARS-CoV-2病毒药物筛选的分子和细胞水平生物实测验证提供更多候选化合物。TargetMol 的药物虚拟筛选团队关注到8个抗SARS-CoV-2相关蛋白靶点（RBD、ACE2、Mpro（又名3CLpro）、PLpro、nsp16、X 结构域、RdRp（又名nsp12）、nsp15）的结构信息后，就迅速投入到抗COVID-19病毒靶标虚拟筛选工作中，选用TargetMol 化合物库进行虚拟筛选，基于虚拟筛选结果，Part2收录了具有抗COVID-19 CADD 活性的化合物，希望我们的工作可以为成功开发抗COVID-19药物并攻克疫情助一臂之力！ 我们将依据科研进展保持抗COVID-19化合物库的更新，一起为阻击新型冠状病毒疫情发展贡献力量。
陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。
产品编号: L1710
规格
30 μL x 10 mM (in DMSO)
50 μL x 10 mM (in DMSO)
100 μL x 10 mM (in DMSO)
250 μL x 10 mM (in DMSO)
特别折扣
等您来询问！
等您来询问！
技术资料
陶术生物化合物库目录(60.2 MB) 
库化合物信息
Excel 
SDF 产品描述
产品描述:
- 1133种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；
- 包括Lopinavir/Ritonavir（克力芝）、Chloroquine diphosphate（二磷酸氯喹，与Remdesivir联用）、Polydatin（虎杖苷，与Mpro结合较好，可能对病毒有抑制作用）等化合物；
- 信息详尽：化合物结构、靶点信息、活性描述等，为活性实验开展提供参考；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
化合物库定制
我们的化合物库可以灵活定制！ 了解更多
化合物库咨询
化合物库组成
Autophagy
Endogenous Metabolite
Apoptosis
Antibacterial
HIV Protease
Others
Antibiotic
DNA/RNA Synthesis
Influenza Virus
SARS-CoV
HCV Protease
Parasite
Reactive Oxygen Species
Reverse Transcriptase
HBV
Potassium Channel
Calcium Channel
Adrenergic Receptor
Antifungal
RAAS
HSV
5-HT Receptor
Cytochromes P450
COX
NF-κB
Ferroptosis
Antioxidant
PI3K
Histamine Receptor
Nucleoside Antimetabolite/Analog
AChR
Mitophagy
VEGFR
Dopamine Receptor
Histone Methyltransferase
Antiviral
Dehydrogenase
Virus Protease
PDE
Prostaglandin Receptor
CCR
Epigenetic Reader Domain
Sodium Channel
PKC
Topoisomerase
Antifection
EGFR
TNF
c-Kit
PDGFR
HDAC
FLT
Proteasome
Phosphatase
PPAR
CDK
TLR
JAK
mTOR
Akt
ribosome
Src
Adenosine Receptor
Caspase
AMPK
c-Met/HGFR
Estrogen Receptor/ERR
Raf
STAT
FGFR
Transferase
Integrin
Tyrosine Kinases
Wnt/beta-catenin
Opioid Receptor
MMP
Bcl-2 Family
Phospholipase
HMG-CoA Reductase
ATPase
PROTACs
DHFR
p38 MAPK
Estrogen/progestogen Receptor
P2Y Receptor
GSK-3
Antifolate
ERK
Glucocorticoid Receptor
Bcr-Abl
FAAH
Cholinesterase (ChE)
Interleukin
TGF-beta/Smad
GABA Receptor
MEK
Ras
TAM Receptor
HIF/HIF Prolyl-Hydroxylase
Carbonic Anhydrase
Reductase
MRP
TRP/TRPV Channel
iGluR
Gamma-secretase
Drug Metabolite
P-gp
HSP
Sirtuin
Nrf2
c-RET
Cannabinoid Receptor
Microtubule Associated
Tyrosinase
Thrombin
NOS
DNA-PK
NADPH
JNK
PKA
Rho
Serine Protease
Serine/threonin kinase
Cysteine Protease
MAO
E1/E2/E3 Enzyme
NMDAR
Mitochondrial Metabolism
Glucosidase
ROS
Fatty Acid Synthase
CXCR
Lipoxygenase
IGF-1R
Norepinephrine
DNA
GluCls
Beta Amyloid
c-Fms
GPR
IRAK
NO Synthase
ADC Linker
Proton pump
MicroRNA
Amino Acids and Derivatives
LPL Receptor
Lipase
CaSR
PARP
Serotonin Transporter
NAMPT
Glucokinase
CSF-1R
P2X Receptor
DPP-4
IL Receptor
PTEN
OX Receptor
Chk
GluR
CaMK
Androgen Receptor
Telomerase
SGLT
Trk receptor
Histone Acetyltransferase
transporter
PAI-1
Casein Kinase
RSV
IκB/IKK
ATM/ATR
Acetyl-CoA Carboxylase
Ligand for E3 Ligase
CRISPR/Cas9
PDK
Hydroxylase
PLK
HIF
Gap Junction Protein
Platelet aggregation
DNA Methyltransferase
S6 Kinase
Protease-activated Receptor
Lysosomal Autophagy
FAK
NOD-like Receptor (NLR)
p53
PD-1/PD-L1
Kinesin
S1P Receptor
HER
Thyroid hormone receptor(THR)
Mdm2
Chloride channel
Taste receptor
NPC1L1
RAR/RXR
ROR
NEDD8
CRM1
Ligands for Target Protein for PROTAC
YAP
IFNAR
Na+/Ca2+ Exchanger
Cell wall
CETP
PERK
gp120/CD4
Tie-2
Glutathione Peroxidase
TOPK
GTPase
VDA
Melatonin Receptor
GNRH Receptor
Cholecystokinin Receptor
Hck
Cell Cycle Arrest
FXR
Stemness kinase
Glutaminase
IAP
IRE1
Annexin A
Adiponectin Receptor
UGT
Fas/FasL
LDL
MT Receptor
Phosphorylase
DNA gyrase
ABC Transporter
Molecular Glues
Guanylate cyclase
Integrase
PROTAC Linker
Thioredoxin
PAK
Bombesin Receptor
Hedgehog/Smoothened
Stearoyl-CoA Desaturase (SCD)
Bradykinin Receptor
ACK1
Vasopressin Receptor
Endothelin Receptor
Aurora Kinase
cAMP
ATP Citrate Lyase
Lipid
PGE Synthase
MAPK
Glutathione reductase
OAT
MNK
Survivin
Acyltransferase
Aminopeptidase
GPCR19
Decarboxylase
ASK
ALK
Pyroptosis
Neprilysin
GST
Retinoid Receptor
Aromatase
LPA Receptor
PI4K
Complement System
Discoidin Domain Receptor (DDR)
Neurokinin receptor
Syk
NADPH-oxidase
Sigma receptor
AhR
CFTR
MLK
ADC Cytotoxin
BTK
PGC-1α
化合物库信息示例
| Empty | 99-66-1 | 99-24-1 | 989-51-5 | 987-65-5 | 98665-22-6 | 97-77-8 | 97322-87-7 | 97230-46-1 | 97-18-7 | 96946-42-8 | Empty |
| Valproic Acid | Methyl gallate | (-)-Epigallocatechin Gallate | ATP disodium salt | Ganoderic acid G | Disulfiram | Troglitazone | Picfeltarraenin IB | Bithionol | Cisatracurium besylate | ||
| Empty | 96829-58-2 | 96574-01-5 | 96392-15-3 | 96187-53-0 | 961-29-5 | 960374-59-8 | 96020-91-6 | 95789-30-3 | 957054-30-7 | 95635-56-6 | Empty |
| Orlistat | Salvianolic acid A | PD 117519 | Brequinar | Isoliquiritigenin | ONX-0914 | Eflornithine hydrochloride hydrate | Cefotiam Hexetil Hydrochloride | Pictilisib | Ranolazine dihydrochloride | ||
| Empty | 95635-55-5 | 955977-50-1 | 951-78-0 | 951-77-9 | 95058-81-4 | 94749-08-3 | 94492-24-7 | 944328-88-5 | 94367-43-8 | 94367-42-7 | Empty |
| Ranolazine | PI-3065 | 2'-Deoxyuridine | 2'-Deoxycytidine | Gemcitabine | Salmeterol Xinafoate | 2'-acetylacteoside | QS11 | (Iso)-Isomucronulatol 7-O-glucoside | Methylnissolin-3-O-glucoside | ||
| Empty | 943319-70-8 | 942183-80-4 | 941678-49-5 | 94079-81-9 | 93957-55-2 | 937272-79-2 | 93675-88-8 | 936091-26-8 | 93-39-0 | 929016-96-6 | Empty |
| Ponatinib | SCH772984 | Ruxolitinib | Poliumoside | Fluvastatin sodium | Pacritinib | Forsythoside E | Fedratinib | Skimmin | Pracinostat | ||
| Empty | 92636-39-0 | 923604-59-5 | 923564-51-6 | 923562-23-6 | 92262-58-3 | 920509-32-6 | 919351-41-0 | 918505-84-7 | 91832-40-5 | 917909-71-8 | Empty |
| (6R,7S)-Cefminox sodium heptahydrate | Simeprevir | Navitoclax | FLT3-IN-2 | Valrocemide | Resmetirom | AZD1283 | PLX-4720 | Cefdinir | BIT225 | ||
| Empty | 917389-32-3 | 917111-44-5 | 916170-19-9 | 91599-74-5 | 913611-97-9 | 908-54-3 | 90729-43-4 | 905579-51-3 | 901751-47-1 | 89919-62-0 | Empty |
| Letermovir | Lexibulin | AC-55541 | Benidipine hydrochloride | Brexpiprazole | Diminazene Aceturate | Ebastine | Pevonedistat | iCRT3 | 3,5-O-Dicaffeoylquinic acid | ||
| Empty | 897016-82-9 | 894187-61-2 | 89396-94-1 | 89226-75-5 | 89226-50-6 | 890-38-0 | 88889-14-9 | 885101-89-3 | 88495-63-0 | 882663-88-9 | Empty |
| Tirbanibulin | STF-118804 | Imidapril hydrochloride | Manidipine dihydrochloride | Manidipine | 2'-Deoxyinosine | Fosinopril sodium | GW9508 | Artesunate | AMG-47a | ||
| Empty | 88-04-0 | 87-89-8 | 87848-99-5 | 87-78-5 | 877822-41-8 | 875320-29-9 | 874911-96-3 | 874484-20-5 | 87-42-3 | 87333-19-5 | Empty |
| Chloroxylenol | i-Inositol | Acrivastine | DL-Mannitol | Eupalinolide B | Quisinostat | ZK 756326 | S29434 | 6-Chloropurine | Ramipril |
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