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自噬库 
Autophagy Compound Library
产品编号: L3200
自噬是一个涉及到细胞自身物质或结构被溶酶体或液泡分解的过程。先是内质网脱落的双层膜包裹细胞内部分受损或老化的细胞器、蛋白质等成分形成自噬体，后与溶酶体或液泡融合降解其所包裹的内容物，以实现细胞本身的代谢需要和某些细胞器的更新。细胞自噬与细胞凋亡、细胞衰老一样，是十分重要的生物学现象，参与生物的发育、生长等多种过程，细胞自噬的异常导致癌细胞的出现。 TargetMol 自噬库集合了文献报道的 1470 种细胞自噬相关的生物活性小分子化合物，可用于细胞自噬机理研究和靶向药物筛选。
陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。
产品编号: L3200
规格
1 mg
30 μL x 10 mM (in DMSO)
50 μL x 10 mM (in DMSO)
100 μL x 10 mM (in DMSO)
250 μL x 10 mM (in DMSO)
特别折扣
等您来询问！
等您来询问！
技术资料
陶术生物化合物库目录(60.2 MB) 
库化合物信息
Excel 
SDF 产品描述
产品描述:
- 1470种细胞自噬相关的生物活性小分子化合物的特有集合，用于自噬相关的研究，用于高通量、高内涵筛选 ;
- 产品经过临床验证和临床实验，具有生物安全保障和一定的生物活性 ;
- 是研究细胞自噬的机理以及药物靶向研究的有效工具 ;
- 活性包括自噬诱导、自噬抑制、蛋白酶体、HIF、E3 Ligase、mTOR等 ;
- 结构多样，药效显著，可渗透细胞 ;
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等 ;
- NMR和HPLC检测技术保证产品高纯度和高质量 ;
- 所有化合物现货供应。
化合物库定制
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化合物库组成
Autophagy
Apoptosis
PI3K
mTOR
Akt
Antibacterial
AMPK
GSK-3
Endogenous Metabolite
Antibiotic
Mitophagy
CDK
p38 MAPK
CXCR
NF-κB
HIV Protease
HDAC
DNA-PK
Parasite
ERK
Ferroptosis
Reactive Oxygen Species
Raf
S6 Kinase
VEGFR
Potassium Channel
ATM/ATR
MEK
DNA/RNA Synthesis
PDK
Src
PKC
Adrenergic Receptor
Cytochromes P450
COX
Retinoid Receptor
Bcr-Abl
PDGFR
EGFR
LRRK2
PKA
Calcium Channel
FLT
c-Kit
JNK
Virus Protease
PPAR
Caspase
Topoisomerase
Aurora Kinase
Influenza Virus
AChR
CFTR
STAT
PI4K
5-HT Receptor
TNF
Estrogen/progestogen Receptor
Antifungal
SARS-CoV
FGFR
HMG-CoA Reductase
Dehydrogenase
Wnt/beta-catenin
FXR
FAAH
CaMK
Bcl-2 Family
Casein Kinase
Ras
PDE
JAK
MMP
Nrf2
Microtubule Associated
HSV
Dopamine Receptor
PERK
ROCK
IL Receptor
TLR
Proteasome
Mitochondrial Metabolism
IGF-1R
TGF-beta/Smad
MAPK
HIF/HIF Prolyl-Hydroxylase
p53
ATPase
Estrogen Receptor/ERR
PARP
Nucleoside Antimetabolite/Analog
TRP/TRPV Channel
Glucocorticoid Receptor
Chk
Lipoxygenase
Sirtuin
c-RET
Sodium Channel
Proton pump
Antioxidant
Rho
PTEN
Epigenetic Reader Domain
HSP
ALK
IκB/IKK
GABA Receptor
HIF
c-Met/HGFR
NADPH
Histamine Receptor
Phosphatase
c-Myc
SIK
P-gp
Trk receptor
MELK
Beta Amyloid
Histone Methyltransferase
HCV Protease
Integrin
Adenosine Receptor
DYRK
MRP
Tyrosine Kinases
Serine/threonin kinase
Glucokinase
Antifection
ROS
Opioid Receptor
DUB
Prostaglandin Receptor
transporter
Phospholipase
SGK
FAK
NOS
Carbonic Anhydrase
DHFR
DNA Alkylator/Crosslinker
RAAS
Progesterone Receptor
Pim
Serotonin Transporter
Cysteine Protease
MAO
RIP kinase
LDL
Gamma-secretase
Hedgehog/Smoothened
GluR
Androgen Receptor
Interleukin
Reverse Transcriptase
c-Fms
ribosome
Cannabinoid Receptor
DNA Methyltransferase
ROS Kinase
NO Synthase
ADC Cytotoxin
Transferase
Dynamin
Amino Acids and Derivatives
Glutathione Peroxidase
GTPase
HBV
Antifolate
Aryl Hydrocarbon Receptor
P2X Receptor
ABC Transporter
DPP-4
Fatty Acid Synthase
DNA
CRISPR/Cas9
PLK
Syk
NOD
Tyrosinase
HER
S1P Receptor
Mdm2
NPC1L1
RAR/RXR
ROR
Ligands for Target Protein for PROTAC
YAP
BACE
Cell wall
Tie-2
IAP
iGluR
IRE1
E1/E2/E3 Enzyme
Drug Metabolite
NMDAR
Glucosidase
Monoamine Transporter
DNA Alkylation
CCR
Cholinesterase (ChE)
Norepinephrine
Beta-Secretase
MNK
Antiviral
Histone Acetyltransferase
GPR
ATTECs
BMI-1
Lysosomal Autophagy
AhR
NOD-like Receptor (NLR)
MLK
Kinesin
Monoamine Oxidase
Apelin receptor
Chloride channel
Adenylyl Cyclase
MyD88
Others
Arginase
LPL Receptor
Reductase
Arrestin
Na+/Ca2+ Exchanger
Lipase
gp120/CD4
TOPK
VDA
Melatonin Receptor
Cholecystokinin Receptor
Serine Protease
NAMPT
PYK2
Glutaminase
FOXO1
IDO
CSF-1R
Immunology/Inflammation related
Myosin
Annexin A
UGT
PAFR
GRK
DNA gyrase
Hexokinase
Molecular Glues
Guanylate cyclase
Smo
Vasopressin Receptor
ACK1
Endothelin Receptor
Somatostatin
cAMP
Indoleamine 2,3-Dioxygenase (IDO)
ATP Citrate Lyase
Lipid
BCRP
OXPHOS
Survivin
Acyltransferase
Aminopeptidase
GPCR19
Ephrin Receptor
Decarboxylase
GluCls
Ligand for E3 Ligase
Aromatase
Complement System
Gap Junction Protein
DAPK
Anti-infection
IRAK
Sigma receptor
Thrombin
p97
Imidazoline Receptor
PD-1/PD-L1
BTK
PGC-1α
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