药食同源库

Food as Medicine Compound Library
产品编号: L6300

“药食同源”指许多食物即药物,中国古代医学家将中药的“四性”、“五味”理论运用到食物之中,认为每种食物也具有“四性”、“五味”,古希腊医学家希波克拉底提出“food is medicine”,现代医学认为饮食中包含的食物在控制炎症水平、平衡血糖、调节血压和血脂、帮助消化器官处理和消除代谢废物等方面起着关键作用。国家卫健委2002年公布了86种既是食品又是药品的中药名单,2019年新增6种,2023年新增党参等9种,2024年新增4种。 我们根据国家卫健委公布的药食同源原料以及相关的文献资料,精心筛选1639个药食同源的化合物,因其食物来源的特性,这些化合物安全性得到保证,具有很高的成药潜力,可用于高通量筛选和高内涵筛选。

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L6300
产品编号: L6300
规格
1 mg
30 μL x 10 mM (in DMSO)
50 μL x 10 mM (in DMSO)
100 μL x 10 mM (in DMSO)
250 μL x 10 mM (in DMSO)
特别折扣
等您来询问!
技术资料
产品描述
产品描述:
  • 1639个药食同源化合物的独特集合,可用于高通量筛选和高内涵筛选;
  • 提供产品的来源、化学信息和生物学信息,为筛选提供理论方向和研究基础;
  • 结构多样,药效显著,可渗透细胞;
  • NMR和HPLC技术保证产品高纯度。
优势介绍:

来源多样性
药食同源单体来源包括金银花、山药、甘草、火麻仁、灵芝、葛根等既是食物又是中药材的物质。这些物质的化学成分信息参考Pubmed和知网的文献,以及TCMIP、TCMSP和Pubchem等开源数据库。

 Food as Medicine Compound Library

结构多样性
1、基于MACCS指纹在85%结构相似度阈值下将库中化合物精准划分为971个高纯度类别,平均每类仅含1.7个核心分子,揭示了中药成分的广谱化学空间。

 Food as Medicine Compound Library

2、包含萜类、黄酮类、酚类、生物碱等多种类别,分类详细。

 Food as Medicine Compound Library

优越的成药潜力
TargetMol药食同源库中62%的单体符合“类药五原则”,表现出优越的类药性和成药潜力,是药物筛选和细胞诱导研究的优质工具,为科学家们提供了在药物开发过程中快速筛选和优化候选药物的可能性。

 Food as Medicine Compound Library  Food as Medicine Compound Library
 Food as Medicine Compound Library  Food as Medicine Compound Library
 Food as Medicine Compound Library  Food as Medicine Compound Library

良好的药代动力学性质
采用Qikprop进行性质预测,51%的化合物具有较高的口服吸收潜力,33%的化合物可能具备血脑屏障穿透能力,同时84%的化合物预测无心脏毒性风险,这些化合物展现出良好的成药性和安全性。

 Food as Medicine Compound Library  Food as Medicine Compound Library  Food as Medicine Compound Library
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