高溶解性片段库

High Solubility Fragment Library

产品编号: L7800

FBDD 方法的前提是建立高品质的片段库，片段分子往往需要满足“三规则”，分子量小于300，氢键供体和受体不超过3，可旋转键数目不超过3，cLogP 小于3。高溶解性片段库按照“三规则”建立，绝大部分片段分子量小于300，氢键供体与受体数量均不高于3，且每个片段均测试过溶解度：DMSO （200 mM）与 PBS（1 mM ）。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品编号: L7800

规格

1 mg

5 mg

10 mg

30 μL x 10 mM (in DMSO)

50 μL x 10 mM (in DMSO)

100 μL x 10 mM (in DMSO)

250 μL x 10 mM (in DMSO)

特别折扣
等您来询问！

技术资料

陶术生物化合物库目录(60.2 MB)

化合物库操作手册(635 KB)

库化合物信息

Excel

SDF

产品描述

产品描述:

数量：2725种片段分子合集，数量适中，是FBDD方法新药筛选的有力工具。
药化性质：化合物库依据Fragment的RO3原则构建进行，具有优良的药化性质，便于后续结构优化。
多样性：药效团丰富，极大的覆盖了可能的空间结构。每一个分子在设计之初的时候均考虑了结构的多样性和新颖性。
溶解度：保证在DMSO和PBS buffer中的溶解度：DMSO (200 mM) ，PBS (1 mM)。
适用方法多样：适合SPR，核磁，X射线单晶衍射等多种检测手段进行新药开发。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

Others

Endogenous Metabolite

Antibacterial

Apoptosis

Autophagy

Sodium Channel

ADC Linker

HCV Protease

Antifungal

Antioxidant

Histamine Receptor

COX

Influenza Virus

AChR

Anti-infection

Antibiotic

Ferroptosis

Mitophagy

PPAR

Adrenergic Receptor

MAO

Drug Metabolite

IL Receptor

DNA/RNA Synthesis

AChE

Aromatase

NF-κB

5-HT Receptor

Monoamine Oxidase

HIV Protease

CAT

Carbonic Anhydrase

Dehydrogenase

JNK

Virus Protease

MRP

Tyrosine Kinases

Parasite

Nucleoside Antimetabolite/Analog

TRP/TRPV Channel

ERK

iGluR

Adiponectin receptor

PDE

CDK

DPP-4

Reactive Oxygen Species

JAK

FAAH

MMP

Aurora Kinase

Interleukin

ATP Citrate Lyase

Akt

Acyltransferase

Antiviral

Trk receptor

Free radical scavengers

Reverse Transcriptase

STAT

Retinoid Receptor

AMPK

P450

TNF

Potassium Channel

Platelet aggregation

化合物库信息示例

Empty	99-94-5	99-92-3	99902-72-4	99-88-7	99727-20-5	99-36-5	99347-30-5	99186-25-1	99169-50-3	99155-80-3	Empty
Empty	p-Toluic Acid	Compound Fr13850	Compound Fr12834	Compound Fr13988	Compound Fr12916	Compound Fr14203	Compound Fr12930	Compound Fr12845	Compound Fr12361	Compound Fr13475	Empty
Empty	99-05-8	99-03-6	98-98-6	98-78-2	98634-00-5	98557-04-1	98-55-5	98-53-3	98-17-9	98-10-2	Empty
Empty	Compound PDK0420	Compound Fr14102	PCL 016	Compound Fr14341	Compound Fr13397	Compound Fr13595	α-Terpineol	Compound Fr13989	Compound Fr13962	Benzenesulfonamide	Empty
Empty	98061-39-3	97-99-4	97509-75-6	97339-02-1	97108-50-4	97051-69-9	960079-47-4	95962-95-1	959575-13-4	959236-70-5	Empty
Empty	Compound Fr12515	Compound Fr14057	Compound Fr14099	Compound Fr13555	Compound Fr14488	Compound Fr13290	Compound FL0236	Compound Fr13998	Compound Fr14433	Compound FL0085	Empty
Empty	958443-40-8	958443-30-6	957957-33-4	957942-34-6	95727-77-8	95725-34-1	955-53-3	95539-61-0	95533-25-8	954525-80-5	Empty
Empty	Compound Fr13103	Compound Fr13074	Compound Fr14385	Compound Fr13590	Compound Fr12494	Compound Fr13539	Compound Fr13570	Compound Fr12759	Compound FL0161	Compound Fr12286	Empty
Empty	95373-40-3	953409-00-2	95337-78-3	952182-05-7	95-17-0	951624-83-2	95-14-7	95-13-6	95-11-4	950603-22-2	Empty
Empty	Compound Fr13540	Compound Fr12436	Compound Fr12561	Compound FL0103	Compound Fr13657	Compound Fr12156	Compound Fr14034	Indene	Compound Fr14051	Compound Fr13681	Empty
Empty	950603-21-1	950603-17-5	949922-52-5	949-69-9	946713-86-6	94-64-4	946409-37-6	946409-08-1	945217-60-7	944685-55-6	Empty
Empty	Compound Fr13795	Compound Fr12315	Compound FL0114	Compound Fr13034	Compound Fr12496	N-(2-CHLOROBENZYL)-N-METHYLAMINE	Compound Fr16637	Compound Fr12347	Compound FL0199	Compound Fr13262	Empty
Empty	944450-90-2	944450-84-4	94-26-8	942-24-5	941678-49-5	94-09-7	94-08-6	94015-05-1	93983-13-2	93-98-1	Empty
Empty	Compound Fr12926	Compound Fr13400	Butylparaben	Methyl indole-3-carboxylate	Ruxolitinib	Benzocaine	Compound Fr14017	Compound Fr13728	Compound Fr12975	Compound PDK0404	Empty
Empty	939801-34-0	939-23-1	937796-07-1	937795-86-3	93680-80-9	936-44-7	936083-53-3	936083-51-1	936083-46-4	936083-43-1	Empty
Empty	Compound FL0243	Compound Fr14012	Compound Fr13258	Compound Fr12753	Compound Fr12278	3-PHENYLPYRROLIDINE	Compound Fr12994	Compound Fr13503	Compound Fr12482	Compound Fr12861	Empty

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