天然大环化合物库
MACROx Generation 大环化合物领域在生产用于hit 识别平台的技术方面取得了良好的成果。具有广泛且浅的结合位点的受体通常可以通过大环化合物有效地进行干预。AnalytiCon 成功建立了一个独特的平台，系统而高效地实现对更高结构多样性的访问。模块化组装使得从命中物化合物到先导化合物的快速发展变得更加容易。AnalytiCon 的天然中环和大环化合物库包括植物和微生物来源的天然产物，环大小范围从8到35。其生物活性涵盖了从线虫杀虫到广谱抗菌、抗细胞增殖到胆固醇生物合成抑制等广泛的适应症领域，反映了其高度的结构多样性。
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陶术生物化合物库目录(60.2 MB) 
库化合物信息
Excel 
SDF MACROx Generation Macrocycles field has done well at producing technologies to serve as hit-identification platforms. Receptors with extensive and shallow binding sites are often effectively addressed through macrocyclic compounds. AnalytiCon has managed to establish a unique platform that systematically and efficiently allows access to higher scaffold diversity. The modular assembly makes a fast development from hit compounds to lead compounds easier.
The following examples show the high structural diversity of medium and macrocyclic ring systems included in our collection.
