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细胞重编程化合物库 
Reprogramming Compound Library
产品编号: L8110
细胞重编程指的是已分化的体细胞在一定条件下被逆转恢复到多能或全能性状态的过程。传统的重编程技术存在整合外源基因等问题在临床应用中存在局限性，而小分子化合物诱导多能干细胞的研究开辟了一条全新的体细胞重编程方法。小分子化合物诱导重编程的优点包括：不整合到基因组，无免疫原性；可以透过细胞膜直接作用于靶点，操作方便；效应可逆，可同时调控多个靶点，精确调控细胞命运。小分子化合物诱导的多能干细胞在药物发现、细胞治疗、疾病建模中具有很大的潜力，为治疗重大疾病开辟了新的途径。
TargetMol 细胞重编程化合物库是2240 种细胞重编程相关信号通路的生物活性小分子化合物的特有集合，为细胞重编程研究提供有效工具
陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。
产品编号: L8110
规格
1 mg
30 μL x 10 mM (in DMSO)
50 μL x 10 mM (in DMSO)
100 μL x 10 mM (in DMSO)
250 μL x 10 mM (in DMSO)
特别折扣
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技术资料
陶术生物化合物库目录(60.2 MB) 
库化合物信息
Excel 
SDF 产品描述
产品描述:
- 2240种重编程信号通路相关的生物活性小分子化合物的特有集合，可用于高通量、高内涵筛选；
- 靶点含MEK、TGF-β、GSK3、wnt等；
- 结构多样，药效显著，可渗透细胞；
- 详细的说明书、化合物结构、靶点信息、IC50值、活性描述等；
化合物库定制
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化合物库咨询
化合物库组成
Apoptosis
Autophagy
PI3K
VEGFR
EGFR
HDAC
mTOR
JAK
p38 MAPK
ERK
Akt
Wnt/beta-catenin
STAT
Histone Methyltransferase
Epigenetic Reader Domain
PDGFR
GSK-3
AMPK
Raf
FGFR
Src
CDK
TGF-beta/Smad
NF-κB
Endogenous Metabolite
MAPK
c-Met/HGFR
FLT
c-Kit
Ras
JNK
PKC
ROCK
MEK
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HIF/HIF Prolyl-Hydroxylase
Nucleoside Antimetabolite/Analog
DNA-PK
DNA/RNA Synthesis
Tyrosine Kinases
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Monoamine Oxidase
Parasite
S6 Kinase
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PDK
TNF
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Aurora Kinase
COX
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Influenza Virus
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TLR
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Dehydrogenase
Casein Kinase
Pim
Rho
Histone Acetyltransferase
Mitophagy
Virus Protease
PARP
Gamma-secretase
IGF-1R
Retinoid Receptor
PI4K
PPAR
Caspase
Smo
IL Receptor
Cytochromes P450
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MMP
c-Fms
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TAM Receptor
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ROS
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Microtubule Associated
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transporter
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iGluR
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CRISPR/Cas9
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DAPK
Anti-infection
BMI-1
Protease-activated Receptor
p97
AhR
NOD-like Receptor (NLR)
CFTR
Imidazoline Receptor
Kinesin
S1P Receptor
ADC Cytotoxin
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